Benefits of Oxaloacetate in CNS Disorders, Seizures & Premenstrual Syndrome
- How to employ nutritional compounds to address symptoms of PMS and fatigue
- Learn how to construct nutritional approaches to reduce seizures
- Demonstrate understanding of the biochemical benefits of oxaloacetat
Millions of people use analgesics on a daily basis for pain control. Both prescription and OTC forms are used. This talk will review the clinical and research literature that addresses the type
During ischemia, hypoxia, seizures, strokes, CNS inflammation, brain trauma, diabetes and neurodegenerative conditions, excessive release of glutamate from neurons and astrocytes initiates neuronal degeneration. Controlling glutamate levels in seizure disorders can reduce incidence of seizures. When glutamate is released in the brain synapses, it is usually quickly removed by excitatory amino-acid transporters. The glutamate transporters in the brain capillaries allow unidirectional transport of glutamate out of the brain and into the blood stream down a concentration gradient. The bloodstream enzyme glutamate oxaloacetate transaminase (GOT), when activated by oxaloacetate, decreases glutamate levels in the blood. Decreasing blood glutamate levels produces a large glutamate gradient between the brain and blood, which facilitates the lowering of brain glutamate. Besides neuronal degeneration, brain mitochondrial energy production declines in CNS diseases. Oxaloacetate has therapeutic value not only in energy production, but also in reduction of inflammation, increasing new neuron formation in the brain memory area and in increasing mitochondria in brain neurons.